Each vial contains Polymyxin B sulfate 500,000 units
Dosage Form / Appearance
Injection (freeze-dried injection)
Indications
For adult patients with severe infections caused by Polymyxin B-susceptible and multidrug-resistant Gram-negative bacteria, not suitable for treating urinary tract infections.
Usage & Dosage
Patients with renal insufficiency (CLcr < 60 mL/min): Intravenous injection 15,000-25,000 units/kg daily, administered every 12 hours.
Contraindications
Patients who have had severe allergic reactions to polymyxin antibiotics, patients with myasthenia gravis.
Precautions
Nephrotoxicity/neurotoxicity risk: Renal function must be carefully measured, avoid concurrent use with other neurotoxic and/or nephrotoxic drugs.
Storage Conditions
Unopened: Store between 20° and 25°C. After preparation: Must be refrigerated between 2° and 8°C, discard after 72 hours.